91. Dhanaraju Mandalapu, Xinjian Ji, Jinfeng Chen, Chuchu Guo, Wan-Qiu Liu, Wei Ding, Jiahai Zhou, Qi Zhang#. (2018) Thioesterase-Mediated Synthesis of Teixobactin Analogues: Mechanism and Substrate Specificity. J Org Chem. 83 (13): 7271-7275. 【Link】
87. Xiaolin Zou, Zhen Hui, Robert A. Shepherd, Shuaiqiang Zhao, Yanfei Wu, Zhuanglin Shen, Cuiping Pang, Shipeng Zhou, Zehai Yu, Jiahai Zhou, Bradly S. Moore, Laura M. Sanchez, Xiaoyu Tang #.(2023)Unveiling a CAAX Protease-Like Protein Involved in Didemnin Drug Maturation and Secretion. Adv. Sci. 2023, 2306044. 【Link】
85. Yuanyuan Huang, Yanfei Wu, Han Hu, Bangzhuo Tong, Jie Wang, Siyu Zhang, Yanyi Wang, Jicong Zhang, Yue Yin, Shengkun Dai, Wenjuan Zhao, Bolin An, Jiahua Pu, Yaomin Wang, Chao Peng, Nan Li, Jiahai Zhou#, Yan Tan #, Chao Zhong#. (2023) Accelerating the design of pili-enabled living materials using an integrative technological workflow. Nat Chem Biol. https://doi.org/10.1038/s41589-023-01489-x 【Link】
81. Dong-Dong Wu, Sheng Jin, Ruo-Xiao Cheng, Wen-Jie Cai#, Wen-Long Xue, Qing-Qing Zhang, Le-Jie Yang, Qi Zhu, Meng-Yao Li, Ge Lin, Yi-Zhen Wang, Xue-Pan Mu, Yu Wang, Igor Ying Zhang, Qi Zhang, Ying Chen, Sheng-Yang Cai, Bo Tan, Ye Li, Yun-Qian Chen, Pu-Juan Zhang, Chen Sun, Yue Yin, Ming-Jie Wang, Yi-Zhun Zhu, Bei-Bei Tao, Jia-Hai Zhou#, Wei-Xue Huang#, and Yi-Chun Zhu#. (2023). Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme. Cell Reports, 42, (7): 112750.【Link】
79. Xu X.#, Yang Q., Wang L., Zheng J., Gu Y., Xing X.#, Zhou J.# (2023) Enzymatic hydrolysis on L-azetidine-2-carboxylate ring opening. Catal Sci & Technol, 13: 3953-3962. 【Link】
78. Ohashi, M., D. Tan, J. Lu, C. S. Jamieson, D. Kanayama, J. Zhou#, K. N. Houk# and Y. Tang# (2023) Enzymatic cis-Decalin Formation in Natural Product Biosynthesis. J Am Chem Soc, 145(6): 3301-3305.【Link】
77. Xu, X.#, L. Yang, X. Zhang, X. Xing, J. Zhou# (2023) Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum. Tetrahedron, 130:133174.【Link】
76.Wu P., Y. Gu, L. Liao, Y. Wu, J. Jin, Z. Wang, J. Zhou, S. Shaik#, B. Wang# (2022) Coordination Switch Drives Selective C−S Bond Formation by the Non-heme Sulfoxide Synthases. Angew Chem Int Edit, 61(50): e202214235.【Link】
74.Zhang, J., X. Hou, Z. Chen, Y. Ko, M. W. Ruszczycky, Y. Chen, J. Zhou# and H. W. Liu# (2022) Dioxane bridge formation during the biosynthesis of spectinomycin involves a twitch radical SAM dehydrogenase that may have evolved from an epimerase. J Am Chem Soc, 144(22): 9910-9919.【Link】
73.Huang, X., J. Feng, J. Cui, G. Jiang, W. Harrison, X. Zang, J. Zhou, B. Wang# and H. Zhao# (2022) Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition. Nat Catal, 5: 586–593.【Link】
72.Zhang, X., Z. Xu, J. Zhou, X. Xing# and L. Li# (2022) Enhancement of protein crystallization using nano-sized metal–organic framework. Crystals, 12(5): 578.【Link】
71.Lee, Y. H., X. Hou, R. Chen, J. Feng, X. Liu, M. W. Ruszczycky, J. M. Gao#, B. Wang#, J. Zhou# and H. W. Liu# (2022) Radical S-Adenosyl methionine enzyme BlsE catalyzes a radical-mediated 1,2-diol dehydration during the biosynthesis of Blasticidin S. J Am Chem Soc, 144(10): 4478-4486.【Link】
70.金交羽,周佳海(2022),Z-基因组的生物合成奥秘被揭示,合成生物学,3(1): 1-5.【Link】
69.Chen, T., Z. Zheng, X. Zhang, J. Chen, L. Cha, Y. Tang, Y. Guo#, J. Zhou#, B. Wang#, H. Liu# and W. Chang# (2022) Deciphering the reaction pathway of mononuclear iron enzyme-catalyzed N≡C triple bond formation in isocyanide lipopeptide and polyketide biosynthesis. Acs Catal, 12(4): 2270-2279.【Link】
68.Wu, L., Z. Wang, Y. Cen#, B. Wang# and J. Zhou# (2022) Structural insight into the catalytic mechanism of the endoperoxide synthase FtmOx1. Angew Chem Int Ed Engl, 61(12): e202112063.【Link】
67.Cheng,
Q., Y. Cheung, C. Liu, Q. Xiao, B. Sun, J. Zhou, E. W. C. Chan, R. Zhang
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66.Wen, W., Y. Zhang, Y. Zhang, Q. Yu, C. Jiang, M. Tang, J. Pu, L. Wu, Y. Zhao, T. Shi, J. Zhou# and G. Tang# (2021) Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12(1): 7085.【Link】
65.Li, S., P. D. Bury, F. Huang, J. Guo, G. Sun, A. Reva, C. Huang, X. Jian, Y. Li, J. Zhou, Z. Deng, F. J. Leeper#, P. F. Leadlay#, M. V. B. Dias# and Y. Sun# (2021) Mechanistic insights into dideoxygenation in gentamicin biosynthesis. Acs Catal, 11(19): 12274-12283.【Link】
64.Xie, L., X. Zang, W. Cheng, Z. Zhang, J. Zhou#, M. Chen# and Y. Tang# (2021) Harzianic acid from Trichoderma afroharzianum is a natural product inhibitor of acetohydroxyacid synthase. J Am Chem Soc, 143(25): 9575-9584.【Link】
63.Xiang, M. Wang, Wu, Z. Lu, J. Tang, J. Zhou, W. Huang#, and G. Zhang# (2021) Structural insights into xylanase mutant 254RL1 for improved activity and lower pH optimum, Enzyme Microb Technol, 147: 109786.【Link】
62.Liu, N., L. Wu, J. Feng, X. Sheng#, J. Li, X. Chen, J. Li, W. Liu, J. Zhou#, Q. Wu#, and D. Zhu# (2021) Crystal structures and catalytic mechanism of L-erythro-3,5-diaminohexanoate dehydrogenase and rational engineering for asymmetric synthesis of β-amino acids, Angew Chem Int Ed, 60: 10203-10.【Link】
61.Gao, D., C. S. Jamieson, G. Wang, Y. Yan, J. Zhou#, K. N. Houk#, and Y. Tang# (2021) A polyketide cyclase that forms medium-ring lactones. J Am Chem Soc, 143: 80-84.【Link】
60.Chen, T., J. Chen, Y. Tang, J. Zhou#, Y. Guo# and W. Chang# (2021) Current understanding toward isonitrile group biosynthesis and mechanism. Chin J Chem, 39(2): 463-472.【Link】
59.Yan, Y., X. Zang, C. S. Jamieson, H. Lin, K. N. Houk, J. Zhou# and Y. Tang# (2020). Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance. Chem Sci, 11(35): 9554-9562.【Link】
58.Ohashi, M., C. S. Jamieson, Y. Cai, D. Tan, D. Kanayama, M. C. Tang, S. M. Anthony, J. V. Chari, J. S. Barber, E. Picazo, T. B. Kakule, S. Cao, N. K. Garg, J. Zhou#, K. N. Houk# and Y. Tang# (2020) An enzymatic Alder-ene reaction. Nature, 586(7827): 64-69.【Link】
57.Chen, C., L. Su#, L. Wu, J. Zhou and J. Wu# (2020) Enhanced the catalytic efficiency and thermostability of maltooligosyltrehalose synthase from Arthrobacter ramosus by directed evolution. Biochem Eng J, 162(2020):107724.【Link】
56.Cheng, R., L. Wu, R. Lai, C. Peng, N. Naowarojna, W. Hu, X. Li, S. A. Whelan, N. Lee, J. Lopez, C. Zhao, Y. Yong, J. Xue, X. Jiang, M. W. Grinstaff, Z. Deng, J. Chen, Q. Cui#, J. Zhou# and P. Liu# (2020) Single-step replacement of an unreactive C-H bond by a C-S bond using polysulfide as the direct sulfur source in anaerobic ergothioneine biosynthesis. ACS Catal, 10(16): 8981-8994.【Link】
55.Dong, Q., S. Yuan, L. Wu, L. Su, Q. Zhao, J. Wu, W. Huang# and J. Zhou# (2020) Structure-guided engineering of a Thermobifida fusca cutinase for enhanced hydrolysis on natural polyester substrate. Bioresour and Bioprocess, 7(1).【Link】
54.Yang, X., L. Wu, A. Li, L. Ye#, J. Zhou# and H. Yu# (2020) The engineering of decameric D-fructose-6-phosphate aldolase A by combinatorial modulation of inter- and intra-subunit interactions. Chem Commun (Camb), 56(55): 7561-7564.【Link】
53.Li, A., C. G. Acevedo-Rocha, L. D'Amore, J. Chen, Y. Peng, M. Garcia-Borras, C. Gao, J. Zhu, H. Rickerby,S. Osuna#, J. Zhou# and M. T. Reetz# (2020) Regio- and stereoselective steroid hydroxylation at C7 by cytochrome P450 monooxygenase mutants. Angew Chem Int Ed Engl, 59(30): 12499-12505.【Link】
52.Chen, T., J. Chen, Y. Tang, J. Zhou#, Y. Guo# and W. Chang# (2020) Pathway from N-alkylglycine to alkylisonitrile catalyzed by Iron (II) and 2-oxoglutarate-dependent oxygenases. Angew Chem Int Ed Engl, 59(19): 7367-7371.【Link】
51.Cai, Y., Y. Hai, M. Ohashi, C. S. Jamieson, M. Garcia-Borras, K. N. Houk#, J. Zhou# and Y. Tang# (2019) Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat Chem, 11(9): 812-820.【Link】
49.Xu, J., Y. Cen, W. Singh, J. Fan, L. Wu, X. Lin, J. Zhou#, M. Huang#, M. T. Reetz# and Q. Wu# (2019) Stereodivergent protein engineering of a lipase to access all possible stereoisomers of chiral esters with two stereocenters. J Am Chem Soc, 141(19): 7934-7945.【Link】
47.Yan, Y., Q. Liu, X. Zang, S. Yuan, U. Bat-Erdene, C. Nguyen, J. Gan, J. Zhou#, S. E. Jacobsen# and Y. Tang# (2018) Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. Nature, 559(7714): 415-418.【Link】
46.Li, Y., W. Zhang, H. Zhang, W. Tian, L. Wu, S. Wang, M. Zheng, J. Zhang, C. Sun, Z. Deng, Y. Sun, X. Qu# and J. Zhou# (2018) Structural basis of a broadly selective acyltransferase from the polyketide synthase of splenocin. Angew Chem Int Ed Engl, 57(20): 5823-5827.【Link】
45.Sun, Z., L. Wu, M. Bocola, H. C. S. Chan, R. Lonsdale, X. D. Kong, S. Yuan#, J. Zhou# and M. T. Reetz# (2018) Structural and computational insight into the catalytic mechanism of limonene epoxide hydrolase mutants in stereoselective transformations. J Am Chem Soc, 140(1): 310-318.【Link】
44.Yuan, H., J. Zhang, Y. Cai, S. Wu, K. Yang, H. C. S. Chan, W. Huang, W. B. Jin, Y. Li, Y. Yin, Y. Igarashi, S. Yuan#, J. Zhou# and G. Tang# (2017) GyrI-like proteins catalyze cyclopropanoid hydrolysis to confer cellular protection. Nat Commun, 8(1): 1485.【Link】
43.Li, M., Z. Zhang, X. Kong, H. Yu, J. Zhou# and J. Xu# (2017) Engineering streptomyces coelicolor carbonyl reductase for efficient atorvastatin precursor synthesis. Appl Environ Microbiol, 83(12).【Link】
42.Zhang, J., N. Liu, R. A. Cacho, Z. Gong, Z. Liu, W. Qin, C. Tang, Y. Tang# and J. Zhou# (2016). Structural basis of nonribosomal peptide macrocyclization in fungi. Nat Chem Biol, 12(12): 1001-1003.【Link】
41.Chen, W., Y. Li, J. Li, L. Wu, Y. Li, R. Wang, Z. Deng# and J. Zhou# (2016) An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis. Protein Cell, 7(9): 673-683.【Link】
40.Zhu, H., G. Xu, K. Zhang, X. Kong, R. Han, J. Zhou# and Y. Ni# (2016). Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding. Sci Rep, 6: 27779.【Link】
39.Zhou, M., L. Xie, Z. Yang, J. Zhou# and J. Xie# (2017) Lysine succinylation of Mycobacterium tuberculosis isocitrate lyase (ICL) fine-tunes the microbial resistance to antibiotics. J Biomol Struct Dyn, 35(5): 1030-1041.【Link】
38.Sun, Z., R. Lonsdale, A. Ilie, G. Li, J. Zhou and M. T. Reetz (2016) Catalytic asymmetric reduction of difficult-to-reduce ketones: triple-code saturation mutagenesis of an alcohol dehydrogenase. ACS Catal, 6(3): 1598-1605.【Link】
37.Sun, Z., R. Lonsdale, L. Wu, G. Li, A. Li, J. Wang, J. Zhou# and M. T. Reetz# (2016) Structure-guided triple-code saturation mutagenesis: efficient tuning of the stereoselectivity of an epoxide hydrolase. Acs Catal, 6(3): 1590-1597.【Link】
36.Luan, Z., F. Li, S. Dou, Q. Chen, X. Kong, J. Zhou, H. Yu# and J. Xu# (2015) Substrate channel evolution of an esterase for the synthesis of cilastatin. Catal Sci & Technol, 5(5): 2622-2629.【Link】
35.Kong, X., H. Yu, S. Yang, J. Zhou, B. Zeng and J. Xu (2015) Chemoenzymatic synthesis of (R)- and (S)-propranolol using an engineered epoxide hydrolase with a high turnover number. Journal of Molecular Catalysis B: Enzymatic, 122: 275-281.【Link】
34.Chen, J., X. Luo, Q. Chen, J. Pan#, J. Zhou and J. Xu# (2015) Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala. Bioresour and Bioprocess, 2(1): 39.【Link】
33.Sun, Z., R. Lonsdale, X. Kong, J. Xu, J. Zhou# and M. T. Reetz# (2015). Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolution. Angew Chem Int Edit, 54(42): 12410-12415.【Link】
32.Kong, X., S. Yuan, L. Li, S. Chen, J. Xu# and J. Zhou# (2014) Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates. Proc Natl Acad Sci U S A, 111(44): 15717-15722.【Link】
31.Kong, X., Q. Ma, J. Zhou#, B. Zeng# and J. Xu# (2014). A smart library of epoxide hydrolase variants and the top hits for synthesis of (S)-β-blocker precursors. Angew Chem Int Ed Engl, 53(26): 6641-6644.【Link】
30.Luo, X., X. Kong, J. Zhao, Q. Chen, J. Zhou# and J. Xu# (2014) Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp. Biotechnol Bioeng, 111(10): 1920-1930.【Link】
29.Sun, Y., S. Yin, Y. Feng, J. Li, J. Zhou, C. Liu, G. Zhu and Z. Guo (2014) Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad. J Biol Chem, 289(22): 15867-15879.【Link】
28.Dou, S., X. Kong, B. Ma, Q. Chen, J. Zhang, J. Zhou# and J. Xu# (2014) Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition. Biochem Biophys Res Commun, 446(4): 1145-1150.【Link】
27.Li, J., C. Wang, Z. Zhang, Y. Cheng# and J. Zhou# (2014) The structural basis of an NADP(+)-independent dithiol oxidase in FK228 biosynthesis. Sci Rep-Uk, 4.【Link】
26.Zhang, Z., F. Yang, J. Zhang, Q. Tang, J. Li, J. Gu, J. Zhou# and Y. Xu# (2013) Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly. Cell Rep, 5(5): 1269-1278.【Link】
25.Xu, Z., S. Li, J. Li, Y. Li, X. Feng, R. Wang, H. Xu# and J. Zhou# (2013) The structural basis of erwinia rhapontici isomaltulose synthase. Plos One, 8(9).【Link】
24.Ma, J., L. Wu, F. Guo, J. Gu, X. Tang, L. Jiang, J. Liu, J. Zhou# and H. Yu# (2013) Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution. Appl Microbiol Biot, 97(11): 4897-4906.【Link】
23.Yang, F., X. Wang, Z. Zhang, J. Pu, Y. Fan, J. Zhou, C. C. Query and Y. Xu (2013) Splicing proofreading at 5' splice sites by ATPase Prp28p. Nucleic Acids Res, 41(8): 4660-4670.【Link】
22.Sun, Y., H. Song, J. Li, Y. Li, M. Jiang, J. Zhou# and Z. Guo# (2013) Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily. PLoS One, 8(4): e63095.【Link】
21.Zhang, Z., X. Zhang, Z. Zhou, H. Hu, M. Liu, B. Zhou# and J. Zhou# (2013) Solution structure of the Magnaporthe oryzae avirulence protein AvrPiz-t. J Biomol Nmr, 55(2): 219-223.【Link】
20.孔旭东,郁惠蕾,周佳海,许建和 (2013),环氧水解酶的结构基础及新酶开发.生物加工过程,11(01): 77-86.【Link】
19.Sun, Y., H. Song, J. Li, M. Jiang, Y. Li, J. Zhou# and Z. Guo# (2012) Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways. Biochemistry, 51(22): 4580-4589.【Link】
18.Diao, L., Q. Dong, Z. Xu, S. Yang, J. Zhou# and R. Freudl# (2012) Functional implementation of the posttranslational SecB-SecA protein-targeting pathway in Bacillus subtilis. Appl Environ Microb, 78(3): 651-659.【Link】
17.Cai, C., L. Wu, C. Li, P. He, J. Zhou and J. Li (2011) Purification, crystallization and preliminary X-ray analysis of phycocyanin and phycoerythrin from Porphyra yezoensis Ueda. Acta Crystallogr Sect F Struct Biol Cryst Commun, 67(5): 579-583.【Link】
16.Zhou, B., X. Li, Y. Li, Y. Xu, Z. Zhang, M. Zhou, X. Zhang, Z. Liu, J. Zhou, C. Cao, B. Yu and R. Wang (2011) Discovery and development of thiazolo [3,2-a] pyrimidinone derivatives as general inhibitors of Bcl-2 family proteins. ChemMedChem, 6(5): 904-921.【Link】
15.Tao, W., Z. Gao, Z. Gao, J. Zhou, Z. Huang, Y. Dong and S. Yu (2011) The 1.6Å resolution structure of activated D138L mutant of catabolite gene activator protein with two cAMP bound in each monomer. Int J Biol Macromol, 48(3): 459-465.【Link】
14.Ren, A., Z. Xia, W. Yu and J. Zhou (2010) Expression, crystallization and preliminary X-ray analysis of an anomeric inverting agarase from Pseudoalteromonas sp. CY24. Acta Crystallogr Sect F Struct Biol Cryst Commun, 66(12): 1635-1639.【Link】
13.Ma, H., J. He, X. Liu, J. Gan, G. Jin and J. Zhou (2010) Surface initiated polymerization from substrates of low initiator density and its applications in biosensors. ACS Appl Mater Interfaces, 2(11): 3223-3230.【Link】
12.朱翠霞,李勋,李雯雯,石志敏,周佳海,王任小 (2010), 三种Bcl-2家族蛋白的表达、纯化和活性分析, 生物医学工程学杂志,27(4): 834-841.【Link】
11.Zheng, C., H. Liu, S. Yuan, J. Zhou and B. Zhang (2010) Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII. Blood, 116(25): 5698-5706.【Link】
10.Zheng, C., H. Liu, J. Zhou and B. Zhang (2010) EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII. Blood, 115(5): 1081-1087.【Link】
9.Han, C., T. Hu, D. Wu, S. Qu, J. Zhou, J. Ding, X. Shen, D. Qu and H. Jiang (2009) X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis. FEBS J, 276(4): 1125-1139.【Link】
8.Lai, L., Z. Xu, J. Zhou, K. D. Lee and G. L. Amidon (2008) Molecular basis of prodrug activation by human valacyclovirase, an α-amino acid ester hydrolase. J Biol Chem, 283(14): 9318-9327.【Link】
7.Xiao, J., H. Xia, J. Zhou, I. F. Azmi, B. A. Davies, D. J. Katzmann and Z. Xu, (2008) Structural basis of Vta1 function in the multivesicular body sorting pathway. Dev Cell, 14(1): 37-49.【Link】
6.Xiao, J., H. Xia, K. Yoshino-Koh, J. Zhou and Z. Xu (2007) Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4. J Mol Biol, 374(3): 655-670.【Link】
5.Zhou, J.*, C. Liu*, S. H. Back, R. L. Clark, D. Peisach, Z. Xu# and R. J. Kaufman# (2006) The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc Natl Acad Sci U S A, 103(39): 14343-14348.【Link】
4.Zhou, J., Z. Xu (2005) The structural view of bacterial translocation-specific chaperone SecB: implications for function. Mol Microbiol, 58(2): 349-357.【Link】
3.Zhou, J., Z. Xu (2003). Structural determinants of SecB recognition by SecA in bacterial protein translocation. Nat Struct Biol, 10(11): 942-947.【Link】
2.Wang, Y.*, J. Zhou*, Y. Wang, J. Bao and H. Chen (2001) Properties of hybrid enzymes between Synechococcus large subunits and higher plant small subunits of ribulose-1,5-bisphosphate carboxylase/oxygenase in Escherichia coli. Arch Biochem Biophys, 396(1): 35-42.【Link】
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