J. Wen#, C. Zhang#, X. Chen#, Z. Dai, M. Li, W. Ma, C. Yam, X. Huang*, C. Xiong*, H. Mei*, An epimer of threose nucleic acid enhances oligonucleotide exonuclease resistance through end capping. Commun Chem. 2025, 8.
Y. Zhao, C. Hu, Y. Gao, C. Liu, M. Li, J. Wen, L. Zhou, H. Mei*, Z. Dai*, Polyacrylamide-Grafted MXenes Prepared via on-Surface Polymerization Demonstrated Enhanced Aqueous Dispersion and Colloidal Stability. Chem. Eur. J. 2025, 31, e202404421.
H. Fan#*, L. Wang#, X. Zeng, C. Xiong, D. Yu, X. Zhang, J. Chen, Z. Meng, A. Campbell, W. Huang, H. Mei*, H. Sun*, Redox-Inducible Radiomimetic Photosensitizers Selectively Suppress Cancer Cell Proliferation by Damaging DNA through Radical Cation Chemistry. Angew. Chem. Int. Ed. 2025, 64, e202413352.
J. Xu, H. Chun*, L. Wang, H. Mei, S. Chen*, X. Huang*, DNA microarray chips: Fabrication and cutting-edge applications. Chemical Engineering Journal. 2024, 499, 155937.
J. Xu, Y. Wang, X. Chen, L. Wang, H. Zhou, H. Mei*, S. Chen*, X. Huang*, "Multi-layer" encryption of medical data in DNA for highly-secure storage. Materials Today Bio. 2024, 28, 101221.
J. Guo#, S. Chen#, Y. Onishi, Q. Shi, Y. Song, H. Mei, L. Chen, E. T. Kool*, R. Zhu*, RNA Control via Redox-Responsive Acylation. Angew. Chem. Int. Ed. 2024, 21, e202402178.
H. Wang#, W. Zhu#, C. Wang, X. Li, L. Wang, B. Huo, H. Mei, A. Zhu, G. Zhang, L. Li*, Locating, tracing and sequencing multiple expanded genetic letters in complex DNA context via a bridge-base approach. Nucleic Acids Research. 2023, 51, e52.
B. Huo, X. Zhang, C. Wang, H. Wang, G. Zhu, W. Zhu, A. Zhu, H. Mei, L. Li*, Mechanistic Insight into the Photoinduced Damage of an Unnatural Base Pair. Chem. Eur. J. 2022, 28, e202201730.
H. Mei, S. Budow-Busse, D. Kondhare, H. Eickmeier, H. Reuter, F. Seela*, The 2′-deoxyribofuranoside of 3-phenyltetrahydropyrimido[4,5-c]pyridazin-7-one: a bicyclic nucleoside with sugar residues in N and S conformations, and its molecular recognition. Acta Cryst. 2022, 78, 382-389.
Q. Wen, Y. Yao, X. Li, Z. Hu, H. Mei, H. Gan*, Chromatin replication and parental histone allocation. Genome Instab. Dis. 2021, 2, 51-58.
Y. Bai, P. Nie, C. Xiong, J. Wen, H. Gan, Q. Ma, Z. Hu, X. Li, T. Yu, J. Huang*, H. Mei*, Construction of Synthetic Life Forms with Genetic Materials Comprising Unnatural Nucleic Acids (in Chinese), 以非天然核酸为遗传物质的人工生命构建，Chin. Sci. Bull. 2021, 66, 347-355
P. Nie, Y. Bai, H. Mei* Synthetic Life with Alternative Nucleic Acids as Genetic Materials. Molecules. 2020, 25, 3483.
H. Mei, Y. Wang, E. J. Yik, J. C. Chaput*, Synthesis and polymerase recognition of a pyrrolocytidine TNA triphosphate. Biopolymers. 2020, 112, e23388.
H. Mei*, J. C. Chaput*, Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue.Methods Mol. Biol. 2019,1973, 27-37. (Invited Book Chapter)
X. Guo, P. Leonard, S. A. Ingale, J. Liu, H. Mei, M. Sieg, F. Seela*, 5-Aza-7-deaza-2'-deoxyguanosine and 2'-Deoxycytidine form Programmable Silver-Mediated Base Pairs with Metal Ions in the Core of the DNA Double Helix. Chem. Eur. J. 2018, 24, 8883-8892.
H. Mei, J. C. Chaput*, Expanding the Chemical Diversity of TNA with tUTP Derivatives that are Substrates for a TNA Polymerase. Chem. Commun. 2018, 54, 1237-1240.
H. Mei#, J. Liao#, R. M. Jimenez, Y. Wang, S. Bala, C. McCloskey, C. Switzer, J. C. Chaput*, Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7‑Deaza-7-Substituted Guanosine Residues. J. Am. Chem. Soc. 2018, 140, 5706-5713.
H. Mei#, C. Shi#, R. M. Jimenez, Y. Wang, M. Kardouh, J. C. Chaput*, Synthesis and Polymerase Activity of a Fluorescent Cytidine TNA Triphosphate Analogue.Nucleic Acids Res. 2017, 45, 5629-5638.
S. Bala#, J. Liao#, H. Mei, J. C. Chaput*, Synthesis of α-L-threofuranosyl Nucleoside 3'-Monophosphates, 3'-Phosphoro(2-methyl)imidazolides, and 3'-Triphosphates. J. Org. Chem. 2017, 82, 5910-5916.
S. K. Jana, X. Guo, H. Mei, F. Seela*, Robust Silver-mediated Imidazolo-dC Base Pairs in Metal DNA: Dinuclear Silver Bridges with Exceptional Stability in Double Helices with Parallel and Antiparallel Strand Orientation. Chem. Commun. 2015, 51, 17301-17304.
H. Yang, H. Mei, F. Seela*, Pyrrolo-dC Metal Base Pairs in the Reverse Watson-Crick Double Helix: Capturing of Silver-Ions, Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Metal Ion Binding. Chem. Eur. J. 2015, 21, 10207-10219.
H. Mei, S. A. Ingale, F. Seela*, 3-Phenyl-5,6,7,8-tetrahydropyrimido[4,5-c]pyridazin-7-one as Nucleobase Substitute in DNA: Synthesis of the 2'-Deoxyribonucleoside, Cyclonucleoside Formation and Base Pairing in Oligonucleotides. Tetrahedron, 2015, 71, 6170-6175.
H. Mei, S. A. Ingale, F. Seela*, Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link, Chem. Eur. J. 2014, 20, 16248-16257.
H. Mei, H.Yang, I. Röhl, F. Seela*, Silver Arrays Inside DNA Duplexes Constructed from Silver(I)-Mediated Pyrrolo-dC–Pyrrolo-dC Base Pairs. ChemPlusChem, 2014, 79, 914-918.
H. Mei, I. Röhl, F. Seela*, Ag+-Mediated DNA Base Pairing: Extraordinarily Stable Pyrrolo-dC–Pyrrolo-dC Pairs Binding Two Silver Ions. J. Org. Chem. 2013, 78, 9457-9563.
S. Ingale, H. Mei, P. Leonard, F. Seela*, Ethynyl Side Chain Hydration During Synthesis and Work up of "Clickable" Oligonucleotides: Bypassing Acetyl Group Formation by Triisopropylsilyl Protection. J. Org. Chem. 2013, 78, 11271-11282.
H. Mei, S. A. Ingale, F. Seela*, Pyrene and Bis-Pyrene DNA Nucleobase Conjugates: Excimer and Monomer Fluorescence of Linear and Dendronized Cytosine and 7-Deazaguanine Click Adducts. Tetrahedron. 2013, 69, 4731-4742.
H. Mei, S. Budow, F. Seela*, Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs. Biomacromolecules. 2012, 13, 4196-4204.
F. Seela*, H. Mei, H. Xiong, S. Budow, H. Eickmeier, H. Reuter, 5-Ethynyl-2'-deoxycytidine: A DNA Building Block with a "Clickable" Side Chain. Acta Cryst. 2012, 68, o395-o398.
S. A. Ingale, S. S. Pujari, V. R. Sirivolu, P. Ding, H. Xiong, H. Mei, F. Seela*, 7-Deazapurine and 8-Aza-7-deazapurine Nucleoside and Oligonucleotide Pyrene "Click" Conjugates: Synthesis, Nucleobase Controlled Fluorescence Quenching, and Duplex Stability. J. Org. Chem. 2012, 77, 188-199.
H. Mei#,L. Xing#, L. Cai, H. Jin, P. Zhao, Z. Yang*, L.-R. Zhang, L.-H. Zhang, Studies on the Synthesis of Neamine-dinucleotides and Neamine-PNA Conjugates and their Interaction with RNA. Bioorg. Med. Chem. Lett. 2008, 18,5355-5358.
* Corresponding author, # Co-first authors