Papers

Xiong, X.#, Liu, Y.#, Pu, D., Yang, Z., Bi, Z., Tian, L.*, and Li, X.* “DeSide: A unified deep learning approach for cellular deconvolution of tumor microenvironment.” Proc. Natl. Acad. Sci. USA, 121(46):e2407096121, 2024.

Chang, Z.#, Guo, X.#, Li, X#., Wang, Y.#, Zang, Z., Pei, S., Lu, W., Li, Y., Huang, J. D., Xiao, Y., & Liu, C. “Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization.” Cell, 188(7), 1842–1857.e20., 2025.

Li, X.-Y.#, Jin, T.#, Wang, L.#, Wu, S., Liu, Y., Li, M.*, Han, W.*, and Li, X.* “Deciphering antigen-specific T cell navigation tactics and cancer immune evasion in co-cultures.” Commun. Biol., 8(1):1140, 2025.

Hu, H.#, Tan, T.#, Liu, Y., Liang, W., Zhang, W., Zhang, J., Cui, J.*, Song, J.*, and Li, X.* “Leveraging deep learning to discover interpretable cellular spatial biomarkers for prognostic predictions based on hepatocellular carcinoma histology.” J. Pathol. Clin. Res., 11(4), e70033, 2025.

Tian, L.#, Li, X.#, Qi, F., Tang, Q.-Y., Tang, V., Liu, J., Li, Z., Cheng, X., Li, X., Shi, Y., Liu, H., and Tang, L.-H.* “Harnessing peak transmission around symptom onset for non-pharmaceutical intervention and containment of the COVID-19 pandemic.” Nat. Commun., 12:1147, 2021.

Liang Tian#, Xuefei Li#, Fei Qi, Qian-Yuan Tang, Viola Tang, Jiang Liu, Zhiyuan Li, Xingye Cheng, Xuanxuan Li, Yingchen Shi, Haiguang Liu, Lei-Han Tang*. Harnessing peak transmission around symptom onset for non-pharmaceutical intervention and containment of the COVID-19 pandemic. Nature Communications 2021, 12(1):1147

Xuefei Li#,Tina Gruosso#, Dongmei Zuo, Atilla Omeroglu, Sarkis Meterissian,Marie-Christine Guiot, Adam Salazar, Morag Park*, Herbert Levine*. Infiltration of CD8+ T cells into tumor cell clusters in triple-negative breast cancer. PNAS 2019, 116(9):3678-3687

Xuefei Li#, Mohit Kumar Jolly#, Jason T. George, Kenneth J. Pienta, Herbert Levine*. Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment. Frontiers in Oncology 2019, 9:10;

Xuefei Li#, Rajesh Balagam#, Ting-Fang He, Peter P. Lee, Oleg A. Igoshin*, Herbert Levine*, On the mechanism of long-range orientational order of fibroblasts. PNAS 2017, 114(34):8974-8979

Xuefei Li and Herbert Levine*. Bistability of the cytokine-immune cell network in a cancer microenvironment. Convergent Science Physical Oncology 2017, 3(2): 024002.

Dongya Jia, Xuefei Li, Federico Bocci, Shubham Tripathi, Youyuan Deng, Mohit Kumar Jolly*, José N. Onuchic*, and Herbert Levine*. Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response. Journal of Clinical Medicine 2019, 8(5): 725.

Bin Yu, Mei Yang, Lei Shi, Yandan Yao, Qinqin Jiang, Xuefei Li, Lei-Han Tang, Bo-Jian Zheng, Kwok-Yung Yuen, David K. Smith, Erwei Song, and Jian-Dong Huang. Explicit hypoxia targeting with tumor suppression by creating an “obligate” anaerobic Salmonella Typhimurium strain. Scientific Reports 2012, 2: 436.