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# Co-first author * Corresponding authors
Wu J, Chen Y, Huang Y, Hao B, Dai S, Zhao L, Zhao Z, Zhao C, Zhang L, Li Y, Xu X, Li N, Huang AC, Zhou J, Tan M, Zhu W, Zhao Q*. (2024). The cytosolic aminotransferase VAS1 coordinates aromatic amino acid biosynthesis and metabolism. Science advances, 10(2), eadk0738.
Zhang X, Li P, Wang W, Zhao W, Dai S, Wang J, Li N, Dai Z*. (2024). Self-lysis microbial consortia for predictable multi-proteins assembly. Bioorganic Chemistry, 144, 107117.
Lv Z, Chen L, Chen P, Peng H, Rong Y, Hong W, Zhou Q, Li N, Li B, Paolicelli RC, Zhan Y*. (2024). Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective. Neuron.
Huang Y, Wu Y, Hu H, Tong B, Wang J, Zhang S, Wang Y, Zhang J, Yin Y, Dai S, Zhao W, An B, Pu J, Wang Y, Peng C, Li N, Zhou J, Tan Y, Zhong C*. (2023). Accelerating the design of pili-enabled living materials using an integrative technological workflow. Nature Chemical Biology, 20(2):201-210.
Yang L, Shen J, Liu C, Kuang Z, Tang Y, Qian Z, Guan M, Yang Y, Zhan Y, Li N, Li X*. (2023). Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity. Nature Communications, 14(1), 900.
Gong H, Hu J, Chen H, Rong L, Lin Q, Zhang B, Li N, Huang J*. (2022). Inhibition of Breast Cancer Cell Migration by Serum Obtained from Engineered Salmonella-treated Mouse. British Journal of Bio-Medical Research, 06(1), 1871-1881.
Deng H, Lei Q, Yang N, Dai S, Peng H, Yang K, Xiao Z, Wang D, Yu Z*, Li N*, Li W*. (2022). Expanded Application of a Photoaffinity Probe to Study Epidermal Growth Factor Receptor Tyrosine Kinase with Functional Activity. Analytical Chemistry.
Liao SJ, Yan ZQ, Zhao WL, Li N*. (2022). Engineered Extracellular Vesicles and Cancer Therapy. SCIENCE CHINA Life Sciences.
Jiang J#, Liu Y#, Yang S#, Peng H, Liu J, Cheng Y-X*, Li N*. (2021). Photoaffinity-Based Chemical Proteomics Reveals 7-Oxocallitrisic Acid Targets CPT1A to Trigger Lipogenesis Inhibition. ACS Medicinal Chemistry Letters.
Li X#, Zhou J#, Zhao W#, Wen Q#, Wang W, Peng H, Gao Y, Bouchonville KJ, Offer SM, Chan K, Wang Z*, Li N*, Gan H*. (2021). Defining Proximity Proteomics of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling. Genomics, Proteomics and Bioinformatics.
Yang SX#, Zhao WJ#, Zhu MC#, Hu HJ, Wang WJ, Zang ZS, Jin ML, Bi JC, Huang JD, Liu CL, Li XF, Yin P, Li N*. (2021). Tumor Temporal Proteome Profiling Reveals the Immunological Triple Offensive Induced by Synthetic Anti-Cancer Salmonella. Frontiers in Immunology, 12, 712936.
Hu F#, Wang L#, Hu Y, Wang D, Wang W, Jiang J, Li N*, Yin P*. (2021). A novel framework integrating AI model and enzymological experiments promotes identification of SARS-CoV-2 3CL protease inhibitors and activity-based probe. Briefings in Bioinformatics.
Tang Z#, Gao JX#, Wu J, Zeng GF, Liao Y, Song ZK, Liang X, Hu JY, Hu Y*, Liu MY*, Li N*. (2021). Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage. Stem Cell Research & Therapy.
Wang L#, Huang J#, Yang S, Huang S*, Li N*. (2021). Chemical proteomics techniques and their perspective enabling roles in quantitative engineering biology. Chinese Science Bulletin.
Du J*, Yuan C, Wang WJ, Yu ZT, Hao R, Zhang Y, Guan M, Li N*, Yang H*. (2020). Aptasensor-enabled quantitative analysis of nanosized extracellular vesicles by flow cytometry. Analyst.
Selkrig J, Li N, Hausmann A, Mangan MSJ, Zietek M, Mateus A, Bobonis J, Sueki A, Imamura H, El Debs B, Sigismondo G, Florea BI, Overkleeft HS, Kopitar-Jerala N, Turk B, Beltrao P, Savitski MM, Latz E, Hardt WD, Krijgsveld J*, Typas A*. (2020). Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. Nature Microbiology.
Previous Journal
Articles
Bao X, Guo X, Yin M, Tariq M, Lai Y, Kanwal S, Zhou J, Li N, Lv Y, Pulido-Quetglas C, Wang X, Ji L, Khan MJ, Zhu X, Luo Z, Shao C, Lim DH, Liu X, Li N, Wang W, He M, Liu YL, Ward C, Wang T, Zhang G, Wang D, Yang J, Chen Y, Zhang C, Jauch R, Yang YG, Wang Y, Qin B, Anko ML, Hutchins AP, Sun H, Wang H, Fu XD, Zhang B, Esteban MA.(2018). Capturing the interactome of newly transcribed RNA. Nat Methods. Download
Soriano GP, Besse L, Li N, Kraus M, Besse A, Meeuwenoord N, Bader J, Everts B, den Dulk H, Overkleeft HS, Florea BI, Driessen C. (2016). Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes in particular in redox and energy metabolism. Leukemia. Download
Jiang JB, Kallemeijn WW, Wright DW, van den Nieuwendijk A, Rohde VC, Folch EC, van den Elst H, Florea BI, Scheij S, Donker-Koopman WE, Verhoek M, Li N, Schurmann M, Mink D, Boot RG, Codee JDC, van der Marel GA, Davies GJ, Aerts J, Overkleeft HS. (2015). In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 alpha-L-fucosidases. Chemical Science. Download
Kraus M, Bader J, Geurink PP, Weyburne ES, Mirabella AC, Silzle T, Shabaneh TB, van der Linden WA, de Bruin G, Haile SR, van Rooden E, Appenzeller C, Li N, Kisselev AF, Overkleeft H, Driessen C. (2015). The novel beta 2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells. Haematologica. Download
Li N, Kuo CL, Paniagua G, van den Elst H, Verdoes M, Willems LI, van der Linden WA, Ruben M, van Genderen E, Gubbens J, van Wezel GP, Overkleeft HS and Florea BI. (2013). Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS. Nature Protocols. Download
van der Linden WA, Li N, Hoogendoorn S, Ruben M, Verdoes M, Guo J, Boons GJ, van der Marel GA, Florea BI, Overkleeft HS. (2012). Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study. Bioorganic & Medicinal Chemistry. Download
van der Linden WA, Willems LI, Shabaneh TB, Li N, Ruben M, Florea BI, van der Marel GA, Kaiser M, Kisselev AF, Overkleeft HS. (2012). Discovery of a potent and highly beta 1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones. Organic & Biomolecular Chemistry. Download
Li J, Girard G, Florea BI, Geurink PP, Li N, van der Marel GA, Overhand M, Overkleeft HS, van Wezel GP. (2012). Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach. Organic & Biomolecular Chemistry. Download
Brouwer AJ, Jonker A, Werkhoven P, Kuo E, Li N, Gallastegui N, Kernmink J, Florea BI, Groll M, Overkleeft HS, Liskamp RMJ. (2012). Peptido Sulfonyl Fluorides as New Powerful Proteasome Inhibitors. Journal of Medicinal Chemistry. Download
Stolze SC, Deu E, Kaschani F, Li N, Florea BI, Richau KH, Colby T, van der Hoom RAL, Overkleeft HS, Bogyo M, Kaiser M. (2012). The Antimalarial Natural Product Symplostatin 4 Is a Nanomolar Inhibitor of the Food Vacuole Falcipains. Chemistry & Biology. Download
Willems LI, Li N, Florea BI, Ruben M, van der Marel GA, Overkleeft HS. (2012). Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities. Angewandte Chemie-International Edition. Download
Li N, Overkleeft HS, Florea BI. (2012). Activity-based protein profiling: an enabling technology in chemical biology research. Current Opinion in Chemical Biology. Download
Clerc J, Li N, Krahn D, Groll M, Bachmann AS, Florea BI, Overkleeft HS, Kaiser M. (2011). The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity. Chemical Communications. Download
Willems LI, van der Linden WA, Li N, Li KY, Liu N, Hoogendoorn S, van der Marel GA, Florea BI, Overkleeft HS. (2011). Bioorthogonal chemistry: applications in activity-based protein profiling. Accounts of Chemical Research. Download
Florea BI, Verdoes M, Li N, van der Linden WA, Geurink PP, van den Elst H, Hofmann T, de Ru A, van Veelen PA, Tanaka K, Sasaki K, Murata S, den Dulk H, Brouwer J, Ossendorp FA, Kisselev AF, Overkleeft HS. (2010). Activity-Based Profiling Reveals Reactivity of the Murine Thymoproteasome-Specific Subunit beta 5t. Chemistry & Biology. Download
Geurink PP, Florea BI, Li N, Witte MD, Verasdonck J, Kuo CL, van der Marel GA, Overkleeft HS. (2010). A Cleavable Linker Based on the Levulinoyl Ester for Activity-Based Protein Profiling. Angewandte Chemie-International Edition. Download
Book
Chapters
de Bruin G, Li N, Paniagua G, Willems L, Xin BT, Verdoes M, Geurink P, van der Linden W, van der Stelt M, van der Marel G, Overkleeft HS, Florea BI. Activity-Based Proteasome Profiling in Medicinal Chemistry and Chemical Biology. Concepts and Case Studies in Chemical Biology, 06/2014: pages 177-190, ISBN: 9783527336111
