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co-first author     *Corresponding authors

2024                              



Zhuang Z#, Wan G#, Lu X, Xie L, Yu T* and Tang H*. Metabolic engineering for single-cell protein production from renewable feedstocks and its applications. Advanced Biotechnology, 2024, 2:35.

Bai Z, Guo S, Yang Y, Zhuang Z, Cao W, Yang Y, Yu T, Tang H. Microbial production of food compounds with carbon dioxide and derived low-carbon molecules as substrates. Chinese Journal of Biotechnology, 2024, 40(8):2731-2746.

Zeng T, Jin Z, Zheng S, Yu T, Wu R. Developing BioNavi for Hybrid Retrosynthesis Planning. JACS Au, 2024, 4(7):2492-2502.

Guo S,Zhang Q,Gulikezi·M,YANG Y,Yu T*. Advances in microbial production of liquid biofuels. Synthetic Biology Journal, 2024, 5:1-16.

Tang H#, Wu L#, Guo S#, Cao W, Ma W, Wang X, Shen J, Wang M, Zhang Q, Huang M, Luo X, Zeng J, Keasling J*, Yu T*. Metabolic engineering of carbohydrate-derived foods and chemicals production in yeast. Nature Catalysis2024, 7:21-34.





2023



Wang X, Li Y, Jin Z, Liu , Gao X, Guo S*, Yu T*A novel CRISPR/Cas9 system with high genomic editing efficiency and recyclable auxotrophic selective marker for multiple-step metabolic rewriting in Pichia pastoris. Synthetic and Systems Biotechnology, 2023, 8(3):445-451.


2022



Yu T*, Liu Q, Wang X, Liu X, Chen Y and Nielsen J*. Metabolic reconfiguration enables synthetic reductive metabolism in yeast. Nature Metabolism, 2022, 4(11): 1551-1559.




Zhang H#, Li Z#, Zhou S, Li S, Ran H, Song Z, Yu T & Yin W*. A fungal NRPS-PKS enzyme catalyses the formation of the flavonoid naringenin. Nature Communications, 2022,13(1):6361.


Zheng T#, Zhang M#, Wu L#, Guo S, Liu X, Zhao J, Xue W, Li J, Liu C, Li X, Jiang Q, Bao J, Zeng J*, Yu T* and Xia C*. Upcycling CO2 into energy-rich long-chain compounds via electrochemical and metabolic engineering. Nature Catalysis. 2022, 5:388–396.






Guo S, Wu L, Liu X, Wang B, Yu T*Developing C1-based metabolic network in methylotrophy for biotransformation. Synthetic Biology Journal, 2022, 3(1):116-137.

Selected Publications (Before joining in SIAT):



Yu T#, Dabirian Y#, Liu Q, Siewers V, Nielsen J*. Strategies and Challenges for Metabolic Rewiring. Current Opinion in Systems Biology, 2019, 15:30-38.

Liu Q., Yu T., Li X., Chen Y., Campbell K., Nielsen J., Chen Y*. Rewiring carbon metabolism in yeast for high level production of aromatic chemicals. Nature Communications, 2019, 10(1):4976.

Yu T#, Zhou Y.J.J#, Huang M, Liu Q, Pereira R, David F, Nielsen J*. Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis. Cell, 2018, 174(6):1549-1558.




Yu T., Zhou Y.J.J., Wenning L., Liu Q.L., Krivoruchko A., Siewers V., Nielsen, J., and David, F*. Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nature Communications, 2017,8:15587.

Yu T., Tao Y., Yang M., Chen P., Gao X., Zhang Y., Zhang T., Chen Z., Hou J., Zhang Y., Ruan K., Wang H., Hu R.G.* Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Research. 2014, 24(10):1214-1230.

[1]Method for detecting protein stability and uses thereof, Ronggui Hu, Tao Yu, Yonghui Tao, US20160068861A1.


[2]Fungal cells and methods for production of very long chain fatty acid derived products, Florian David, Verena Siewers, Anastasia KRIVORUCHKO, Leonie WENNING, Tao Yu, Yong-jin ZHOU, Jens Nielsen, US20180112240A1.


[3]Yeast strains and construction methods for the synthesis of ferulic acid and its application in the preparation of ferulic acid and piperine metabolites, Zhehao Jin, Tao Yu, CN116622532A.


[4]A kind of Saccharomyces cerevisiae engineering strain fermented by glucose-ethanol co-carbon source with high geraniol yield, and its construction method and application, Tao YuZhehao Jin, Xuemei Zhao, Fei Tian, CN117126755A.


[5]A recombinant yeast strain for synthesizing aromatic compounds, and its construction method and application, Tao Yu, Zhehao Jin, CN118109326A.