Shenzhen Synthetic Biology Infrastructure
Shenzhen Synthetic Biology Infrastructure

Shenzhen Synthetic Biology Infrastructure(hereinafter referred to as "SSBI" ) is a strategic scientific platform designed to advance future-oriented life sciences research. Integrating the concept of a Cloud Lab for users and an Intelligent Lab for operators, SSBI aims to foster synergy between fundamental scientific research and applied innovation. With its core features of intelligence, automation, and high-throughput capabilities, SSBI provides scientists with a pioneering and systematic research environment. By establishing a "Design-Build-Test-Learn" (DBTL) cycle, the infrastructure enables interdisciplinary research and empowers scientists to unravel the complexities of life sciences.

Accelerating Research with Intelligent Design
Design and Learn Platform of SSBI leverages bioinformatics, mathematical modeling, synthetic biology big data, and artificial intelligence to rapidly generate efficient experimental solutions tailored to specific scientific questions. For example, scientists can use the platform to design complex genetic networks, predict metabolic pathways, or simulate the dynamic behavior of artificial cells. The platform's outputs are directly converted into executable instructions for the Biofoundry Platform, significantly shortening the time from experimental conception to completion. This fully automated workflow allows scientists to focus more on innovation and discovery, enhancing both efficiency and precision.

Flexible Production and High-Throughput Testing for Accelerated Discovery
As the core execution hub of SSBI, the Biofoundry Platform provides scientists with a customizable experimental environment. Equipped with large DNA fragments, high-efficiency strains (such as phages, bacteria, and yeast), and modular automated systems, the platform utilizes a flexible "functional island" architecture to support end-to-end experiments, from genome editing and protein synthesis to cell system construction. Most notably, the platform's flexible production lines can be tailored to meet specific experimental needs, enabling rapid integration of experimental workflows. This combination of high flexibility and high-throughput capabilities ensures the smooth execution of complex research projects.

Multi-Modal Detection for Exploring the Mysteries of Life
The Multi-Modal Analysis Platform offers scientists a powerful suite of tools, integrating protein and metabolite analysis, chassis cell amplification, and advanced imaging systems. This allows for comprehensive, cross-scale characterization of synthetic products, from the molecular to the cellular level. Whether conducting fine-grained single-cell analysis or system-level functional validation, the platform provides high-sensitivity, multi-dimensional data support. By bridging the gap between synthetic biology design and artificial cell construction, this platform equips researchers with the tools to uncover the dynamic mechanisms of life systems.

Driving Breakthroughs in Interdisciplinary Research
The greatest value of SSBI for fundamental scientific research lies in its openness and interdisciplinary applicability. Whether in genomics, synthetic gene network design, biochemical metabolic analysis, or artificial life system assembly and testing, the platform provides scientists with a solid experimental foundation and innovative tools. For instance, in evolutionary biology, researchers can simulate and modify life systems to validate key evolutionary mechanisms. In systems biology, the high-throughput automated workflows enable scientists to explore the dynamics of complex gene networks. By integrating intelligent manufacturing concepts into synthetic biology, SSBI significantly enhances the depth and scope of research, injecting continuous innovation into the life sciences.

Fostering Open Collaboration and International Innovation
As a fully open platform for academia and industry, SSBI provides an equitable and accessible research environment for scientists worldwide. Its Cloud Lab enables researchers to submit experimental requests without geographical constraints, with the intelligent system executing precise automated workflows. SSBI also organizes technical training, project-based experiments, and academic exchanges, fostering an open and collaborative international research ecosystem. By bridging different scientific disciplines and industrial needs, SSBI facilitates the efficient translation of fundamental research into applied technologies.

Why Choose SSBI?
SSBI offers world-class technological infrastructure, comprehensive functional modules, and exceptional user support, providing fundamental research scientists with unparalleled advantages:
1. Comprehensive Support for the Entire Research Cycle: From design to construction and testing, SSBI's one-stop platform eliminates coordination challenges, allowing scientists to focus on innovation.
2. High-Quality, High-Precision Data Acquisition: The multi-modal, cross-scale detection system ensures that every scientific discovery is based on rigorous and comprehensive data.
3. Rapid Experimentation with Flexible Adjustments: The flexible and automated experimental production lines, combined with customizable research capabilities, allow scientists to adjust strategies and iterate rapidly.
4. A Globally Open Platform: SSBI supports collaboration across industries and disciplines, enabling researchers to tackle major scientific challenges in life sciences together.
Find more information in https://infrasynbio.siat.ac.cn/en/platform/our/Biofoundry