Bacterial-based cancer therapy

Through collaborations with other labs at iSynBio,
via quantitative data analysis and
computational modeling study,
we want to understand how the engineered bacteria strains eliminate mice tumors.

cancer-cell EMT and immune infiltration

Investigating the mechanistic links between cancer-cell EMT and immune-infiltration in solid tumors

Infiltration of CAR-T cells in solid tumors

Through coculturing cancer cells and CAR-T cells in vitro, we want to understand how cancer cells hinder the infiltration of CAR-T cells into tumor spheroids.

Grants