Proteome Spatiotemporal Dynamics

Views:821       Publish Time: 2019-06-21

The goal of proteomic spatiotemporal dynamics is to resolve kinetic changes in the proteome in time and space using proteomics techniques. Proteins exist in the form of a complex spatial network structure in the body. The signal transmission between proteins in vivo is essential in a living organism. Therefore, by analyzing the interactions between proteins in the body, we can gain a better understanding of the molecular basis of life; For example, proteomic spatiotemporal dynamics can be used in combination with unnatural amino acids and photo crosslinking technique to study membrane protein interactions (eg, LAT3, BTNL2), and nuclear protein interactions (eg, Mettl14). Besides signal transmission between proteins within an organism, the transmission of protein signals between biological individuals is also necessary for their survival and development, and by understanding these signals, we can better understand host-pathogen interactions. For example, we have used spatiotemporal dynamics to study protein interactions between Salmonella and macrophages at specific time points.  this will be useful for analyzing the molecular basis for bacterial treatment of cancer of how this technique can be used to study interactions between organisms use this technique to study protein interactions between Salmonella and macrophages at specific time points, which can then be used analyze the molecular basis for bacterial treatment of cancer. The analysis of protein interaction between individuals can also help us to better understand the evolutionary process.